Copyright ©The Author(s) 2018.
World J Gastroenterol. Dec 21, 2018; 24(47): 5297-5311
Published online Dec 21, 2018. doi: 10.3748/wjg.v24.i47.5297
Figure 2
Figure 2 Inflammatory cascade responses in the hepatic microenvironment. Crosstalk among parenchymal cells (hepatocytes), non-parenchymal liver cells (Kupffer cells and hepatic stellate cells) and recruited immune cells (macrophages, mast cells, dendritic cells and natural killer cells) plus hepatitis C virus replication in the hepatic microenvironment mediates inflammatory cascade signalling and exacerbates liver injury and disease progression. HSC: Hepatic stellate cells; NK: Natural killer; HCV: Hepatitis C virus.