Copyright ©The Author(s) 2015.
World J Gastroenterol. Jul 7, 2015; 21(25): 7637-7647
Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7637
Table 3 Impact of pretransplant sarcopenia on outcomes after liver transplantation
Ref.nUnit of measureLevel of measureImpact on the post-transplant survivalImpact on the post-transplant infectionImpact on the length of post-transplant hospitalization
Cruz et al[60]234SMI, cm2/m2L3-4SMI was significantly associated with survival post-transplantation (HR, 95%CI: 0.97, 0.94-0.99); P = 0.014)
DiMartini et al[40]338SMI, cm2/m2L3-4Muscle mass was a significant predictor of survival only in men (HR = 0.95, P = 0.01)Muscle mass predicted ICU stay, total length of stay, and days of intubation
Durand et al[7]562TPMT/height, mm/mumbilicusMELD-psoas score was not an independent prognostic factor for post-transplant mortality in pre-MELD and MELD-era cohorts
Englesbe et al[41]163TPA, mm2L4The risk of post-transplantation mortality increased as psoas area decreased (HR = 3.7/1000 mm2 decrease in psoas area; P < 0.0001)
Krell et al[42]207TPA, mm2L4Pretransplant TPA (HR = 0.38, P < 0.01) was an independent risk factor for developing a serious posttransplant infection
Masuda et al[64]204Area of the psoas muscle, cm2L3Sarcopenia was an independent prognostic factor for posttransplant mortality (HR = 2.06, P = 0.047)The rate of postoperative sepsis was higher in sarcopenic patients than in nonsarcopenic patients (17.7% vs 7.4%, P = 0.03)
Montano-Loza et al[45]248SMI, cm2/m2L3L3 SMI and the presence of sarcopenia were not associated with increased mortality after liver transplantationBacterial infections within the first 90 d after liver transplantation were more common in sarcopenic patients than in nonsarcopenic patients (26% vs 15%, P = 0.04)Sarcopenic patients had longer hospital stays (40 ± 4 d vs 25 ± 3 d, P = 0.005) and longer ICU stays (12 ± 2 d vs 6 ± 1 d, P = 0.001) after liver transplantation than nonsarcopenic patients