Inflammatory microenvironment and expression of chemokines in hepatocellular carcinoma

Table 1 Observation of inflammatory cell phenotype in paired tumor and adjacent peritumoral samples, n = 3

Inflammatory cell	Tumor sample	Peritumoral samples	Mean difference	(95%CI)	P
T helper cell	12.09 ± 10.74	20.08 ± 13.31	7.53	(2.75-13.31)	0.005
Cytotoxic T cell	7.25 ± 8.07	6.05 ± 8.41	11.87	(21.60-2.14)	0.800
B cell	2.88 ± 6.36	4.31 ± 6.87	10.87	(19.60-4.07)	0.600
Activated T cell	2.12 ± 2.37	6.96 ± 5.17	5.10	(3.17-7.02)	0.005
NK cell	0.29 ± 1.30	2.30 ± 5.18	1.83	(0.21-3.45)	0.060
Macrophage	9.03 ± 9.97	19.76 ± 9.41	8.07	(4.00-12.13)	0.005
Mast cell	9.00 ± 5.35	10.44 ± 9.00	0.78	(21.07-3.09)	0.600
Neutrophil	1.56 ± 3.22	14.83 ± 14.76	13.28	(8.37-18.19)	0.005
Plasma cell	5.59 ± 7.11	6.50 ± 8.00	0.67	(20.16-4.14)	0.800
iNOS+ cells median (range)	0 (0-3)	10 (6-16)	-	-	0.005
Arginase I+ cells median (range)	1 (0-2)	0 (0-1)	-	-	0.005

Data are expressed as mean ± SD unless otherwise indicated. iNOS: Inducible nitric oxide synthase.