Brief Article
Copyright ©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Jun 28, 2012; 18(24): 3129-3137
Published online Jun 28, 2012. doi: 10.3748/wjg.v18.i24.3129
Figure 2
Figure 2 Tumors in which liver-intestine cadherin was knocked down show fewer invasive characteristics in vivo. Hematoxylin-eosin staining revealed that primary orthotopic tumors (A, B) derived from BGC823 or lenti-liver-intestine cadherin (CDH17)-miR-neg cells spread into the liver (C, D) and lung (E, F) more frequently than those derived from lenti-CDH17-miR-B cells. Nude mice injected with these two types of tumors also showed invasion of the diaphragmatic muscle (G) and spleen (H).