Basic Research
Copyright ©The Author(s) 2003.
World J Gastroenterol. Apr 15, 2003; 9(4): 759-764
Published online Apr 15, 2003. doi: 10.3748/wjg.v9.i4.759
Figure 1
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Figure 1 Rejection grades of grafted liver in different groups. Data were expressed as mean ± SD. I, Wistar-Wistar group; II, SD-Wistar group; III, SD-Wistar + CsA group; IV, LSA + SD-Wistar group; Rejection grades of group IV were significantly lower than that in group II at all but day 1 time point. No sig-nificant discrepancies were found between group IV and group III on day 7 and day 12 time points. aP < 0.05 vs group II, bP > 0.05 vs group III.
Figure 2
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Figure 2 The kinetic change of intragraft IL-2mRNA expres-sion in different groups. I, Wistar-Wistar group; II, SD-Wistar group; III, SD-Wistar + CsA group; IV, LSA + SD-Wistar group; IL-2mRNA expression of group IV were significantly lower than that in group II at all time point (P < 0.05).
Figure 3
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Figure 3 The kinetic change of Intragraft IFN-γ mRNA ex-pression in different groups. I, Wistar-Wistar group; II, SD-Wistar group; III, SD-Wistar + CsA group; IV, LSA + SD-Wistar group; IL-2mRNA expression of group IV were significantly lower than that in group II at all time point (P < 0.05).
Figure 4
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Figure 4 EMSA specific competitive inhibition. Lane 1, nega-tive control; Lane 2, positive control; Lane 3, specific competition; Lane 4, non-specific competition; Lane 5, mutant competition.
Figure 5
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Figure 5 NF-κB activity of splenocytes at different time points after the transplantation. A, Wistar-Wistar group; B, SD-Wistar group; C, SD-Wistar + CsA group; D, LSA + SD-Wistar group; E, the kinetic change of NF-κB activity. NF-κB activity of group IV were significantly lower than that in group II at all time point (P < 0. 05).