Effects of glycyrrhetinic acid on collagen metabolism of hepatic stellate cells at different stages of liver fibrosis in rats

Figure 1 Densitometric analysis of collagenase, type III and I procollagen mRNA Northern blot. The result of Densitometric analysis after normalization against hybridization signals for normal groups was expressed as mean percentage ± SD of the control values (n = 5). The level of types I and III procollagen mRNA expression of HSCs in GA groups was lower than in model groups (^aP < 0.05). For the collagenase mRNA expression of HSCs, there was no significant difference between GA groups and model groups.

Figure 2 Dot blot densitometric analysis of types I and III collagen. The result of densitometric analysis after normalization against hybridization signals for normal groups was expressed as mean percentage ± SD of the control values (n = 5). The level of types I and III collagen densitometric values in GA groups was lower than in model groups (^aP < 0.05).