Observational Study
Copyright ©The Author(s) 2019.
World J Gastroenterol. May 21, 2019; 25(19): 2354-2364
Published online May 21, 2019. doi: 10.3748/wjg.v25.i19.2354
Figure 1
Figure 1 Rate of patients achieving the different therapeutic endpoints after 12 wk of anti-tumor necrosis factor therapy in 40 patients with Crohn’s disease. CDAI: Crohn’s disease activity index; CRP: C-reactive protein; Fcal: Faecal calprotectin; TNF: Tumor necrosis factor.
Figure 2
Figure 2 Level of faecal calprotectin at baseline and after 12 wk of anti-tumor necrosis factor therapy in patients with Crohn’s disease achieving steroids-free remission (Crohn’s disease activity index < 150 and C-reactive protein < 2. 9 mg/L and faecal calprotectin < 250 µg/g with no therapeutic intensification and no surgery) or not at week 52. CFREM: Corticosteroids-free remission.
Figure 3
Figure 3 Positive and negative predictive values of Crohn’s disease activity index, C-reactive protein and faecal calprotectin, alone or combined, after 12 wk of anti-tumor necrosis factor to predict corticosteroids-free remission at week 52. Faecal calprotectin (Fcal) improvement (Fcal < 300 μg/g at W12; or, for patients with initial Fcal < 300 μg/g, at least 50% decrease of Fcal or normalization of Fcal (< 100 μg/g). CDAI: Crohn’s disease activity index; CRP: C-reactive protein; Fcal: Faecal calprotectin.