Case Report
Copyright ©The Author(s) 2016.
World J Gastroenterol. Apr 7, 2016; 22(13): 3687-3692
Published online Apr 7, 2016. doi: 10.3748/wjg.v22.i13.3687
Figure 1
Figure 1 A duodenoscopic image showed an enlarged major papilla with central umbilication and fine nodularity on ampullary orifice (A), endoscopic ultrasonography at the major ampulla revealed a 1. 1 × 0.9-cm, slightly hypoechoic round ampullary mass confined to the submucosa without definite wall disruption or adjacent invasion (B).
Figure 2
Figure 2 Endoscopic papillectomy. Following submucosal injection of 1:10000 diluted epinephrine, snaring papillectomy was performed (A), finally papillectomy induced ulceration is noted without complications (B), following the first papillectomy, a resected papillary roof is noted (C), A whitish and round mass-like lesion was resected by a subsequent second papillectomy (D).
Figure 3
Figure 3 The protruding whitish mass lesion (second papillectomy tissue, Figure 2D) was composed of two lesions that differed in their histological characteristics. Tubular adenoma (solid arrow) and NET [Dotted arrow, hematoxylin-eosin (HE) staining, magnification × 4; A]. The tubular adenoma lesion exhibited round-to-oval enlarged glands with stratified epithelial cells (HE staining, magnification × 100; B). The NET showed cord-like arrangement of monotonous tumor cells (HE staining, magnification × 100; C). Immunohistochemistry showed that the tumor cells were positive for synaptophysin (magnification × 100; D).
Figure 4
Figure 4 Follow-up endoscopic biopsy of the papillectomy site three month later dose not show remnant tumor.