Published online Apr 7, 2016. doi: 10.3748/wjg.v22.i13.3687
Peer-review started: November 4, 2015
First decision: December 15, 2015
Revised: December 17, 2015
Accepted: December 30, 2015
Article in press: December 30, 2015
Published online: April 7, 2016
Ampullary adenoma is a common indication for endoscopic papillectomy. Ampullary neuroendocrine tumor (NET) is a rare disease for which complete surgical resection is the treatment of choice. However, because of the morbidity and mortality associated with surgical resection, endoscopic papillectomy is increasingly used in selected cases of low grade, with no metastasis and no invasion of the pancreatic or bile duct. Also, confirmed and complete endoscopic resection of ampullary NET accompanied by adenoma has not been reported to date. We report herein a rare case of an ampullary NET accompanied with adenoma, which was successfully and completely resected via endoscopic papillectomy. Prior to papillectomy, this case was diagnosed as an ampullary adenoma.
Core tip: In selected cases without metastasis or invasion of the pancreatic and bile duct, endoscopic papillectomy can be a treatment of choice for ampullary neuroendocrine tumor (NET). To the best of our knowledge, the complete cure case of successful endoscopic papillectomy for ampullary NET accompanied with ampullary adenoma has not been reported in the English-language literature. This unusual ampullary NET accompanied with adenoma was successfully treated by endoscopic papillectomy.