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Copyright ©The Author(s) 2016.
World J Gastroenterol. Jan 7, 2016; 22(1): 262-274
Published online Jan 7, 2016. doi: 10.3748/wjg.v22.i1.262
Figure 1
Figure 1 The clinical utility of biomarkers according to typical hepatocellular carcinoma guidelines worldwide. A: Typical hepatocellular carcinoma (HCC) guidelines in Western countries; B: Typical HCC guidelines in Asian countries. 1Alpha-fetoprotein (AFP) alone is not recommended for diagnosis of HCC; the measurement of both AFP and des-γ-carboxyprothrombin (DCP) provides a higher level of sensitivity without decreasing specificity; 2AFP ≥ 400 ng/mL over 1 mo or AFP ≥ 200 ng/mL over 2 mo; 3Optional examinations include computed tomography (CT)-angiography, liver-specific contrast-enhanced magnetic resonance imaging (MRI), contrast ultrasound (US), or liver tumor biopsy.