Gastric myeloid sarcoma without acute myeloblastic leukemia

Figure 1 Endoscopic examination revealed numerous hyperplastic nodules in the stomach. A: Fundus; B: Body; C: Angle; D: Antrum.

Figure 2 Photomicrographs of hyperplastic nodules in gastric biopsy specimens. The gastric biopsies had a decrease in the mucosal glands in the lamina propria and the infiltration of many lymphocytes, including some atypical cells, and strong myeloperoxidase (MPO) and creatine kinase (CK) staining. A: Hematoxylin and eosin (HE) staining, × 100; B: HE staining, × 400; C: MPO staining, × 400; D: CK staining, × 400.

Figure 3 Immunohistochemical characteristics of hyperplastic nodules in gastric biopsy specimens. A: Neoplastic cells had negative staining for cytoplasmic CD3; B: Negative staining for CD79α; C: Strong staining for cytoplasmic CD43; D: Strong staining for CD33; E: Strong staining for CD117; F: Weak staining for CD68; G: Strong staining for CD99; H: Strong staining for Ki67 over 70%. Original magnification for all images, × 400.

Figure 4 Representative images of blood smears and bone marrow biopsies. The images show that the bone marrow is normal without acute myeloblastic leukemia A: Blood smear (Wright and Giemsa stain, × 1000); B: Bone marrow biopsy (Wright and Giemsa staining, × 1000).

Figure 5 Images from abdominal computed tomography scans and positron emission tomography-computed tomography. A and B: Plain computed tomography (CT) scan images; C and D: CT images in the parenchymal phase of contrast enhancement; E and F: Positron emission tomography-CT images.

Figure 6 Endoscopic examination showed that the gastric hyperplastic nodules were removed after chemotherapy. A: Fundus; B: Body; C: Angle; D: Antrum.