Application of metagenomics in the human gut microbiome

Figure 1 Application of metagenomics in the human gut microbiome. In studying the human gut microbiome, metagenomic analysis has the potential to provide sufficient information in the following research areas: The detection of microbial composition and diversity, novel genes, microbial pathways, functional dysbiosis, antibiotic resistance genes, and the determination of interactions and co-evolution between microbiota and host.

Figure 2 Comparison of different gut microbiome study approaches. The characteristics, limitations, and applications of different gut microbiome approaches from cultivation to metabolomics are presented. DGGE: Denaturing gradient gel electrophoresis.