Primary pancreatic paraganglioma: A report of two cases and literature review

Figure 1 Fifty-four-year-old woman felt left upper abdominal pain for 20 d. A: Ultrasonography revealed an ill-defined hypoechoic mass in the pancreatic head (arrows); B: On contrast-enhanced computed tomography, the mass (arrow) in the pancreatic head was found with heterogeneous marked enhancement in the arterial phase, while non-enhancing patchy areas were seen in the tumor (arrowhead); C: Microscopically, the chief cells had round or ovoid nuclei (arrows), arranged in nest-like structures with dilated capillary intervals (hematoxylin-eosin; original magnification, 200 ×); D: Immunohistochemical study revealed positive staining for synaptophysin (200 ×).

Figure 2 Forty-one-year-old woman was found to have an upper abdominal mass on ultrasound examination 6 d earlier. A: On coronal reconstruction imaging, a well-demarcated mass (arrows) was found with marked enhancement in the arterial phase after contrast enhancement; B: Under microscopic examination, a few cells had large nuclei with hyperchromatism and pink cytoplasm, arranged in organ-like or nest-like structures (arrows) (hematoxylin-eosin; original magnification, 200 ×); C: Immunohistochemistry showed positive staining for synaptophysin (200 ×).