Histological mixed-type as an independent prognostic factor in stage I gastric carcinoma

Figure 1 Representative case of mixed-type gastric carcinoma. A 68-year-old man, who underwent curative gastrectomy with lymphadenectomy for mixed-type gastric carcinoma (pT1bN0M0, 75 mm × 45 mm), died of peritoneal recurrence. A: Mixed-type gastric carcinoma consists predominantly of a differentiated component and has < 50% of an undifferentiated component; B: At a higher magnification.

Figure 2 Comparison of cause-specific survival rates of patients in each of the histological subgroups. Four hundred and forty-six patients were divided into four histological subgroups, pure D, pure U, D > U, and U > D groups. Five-year cause-specific survival rates of the patients in each group were analyzed with the Kaplan-Meier method and log rank test. P < 0.05 was considered statistically significant. ^aP < 0.05 vs control; D: Differentiated; U: Undifferentiated.

Figure 3 Comparison of cause-specific survival rates between the histological mixed-type and non-mixed-type in stage I gastric cancer. Five-year cause-specific survival rates in two groups, the mixed-type and the non-mixed-type, were analyzed with the Kaplan-Meier method and log rank test. P < 0.05 was considered statistically significant. P < 0.05 vs control.