Recurrent hepatitis C after liver transplant

Figure 1 Histopathology of fibrosing cholestatic hepatitis C. Histopathology of fibrosing cholestatic hepatitis C demonstrating periportal sinusoidal and pericellular “chicken wire” fibrosis (trichrome, image magnification × 40) (Courtesy of Carl Jacobs, MD, Department of Pathology, Carolinas Medical Center, Charlotte, NC, United States).

Figure 2 Percent of patients with hepatitis C virus RNA. A: Percent of patients with undetectable hepatitis C virus (HCV) RNA treated with transplant viral clearance (TVR) or boceprevir (BOC) plus pegylated-interferon/ribavirin post-liver transplantation[35]; B: Percent of patients on triple therapy (88%, TVR and 12%, BOC) with HCV RNA below level of detection. Sustained viral response rate (SVR4) refers to percent of patients with undetectable HCV RNA 4 wk following completion of 48 wk of treatment[36].