Role of antispasmodics in the treatment of irritable bowel syndrome

Figure 1 The number of short spike bursts measured by colonic intraluminal electromyography[34]. The values were calculated over the period of 15 (A) and 60 min (B). Each group included 8 patients. The 6-h screening session consisted of three 2-h periods: a control period; a period of stress (during which a cold pressor test was performed for 15 min); and a post-prandial period (patients ingested a 800 kcal meal). SSBs: Short spike bursts. ^aP < 0.05 vs normal controls; ^cP < 0.05 vs chronic constipation patients.