Diagnostic accuracy of a new point-of-care screening assay for celiac disease

Figure 1 Celiac disease lateral-flow immunochromatographic assay visual result interpretation. CT: Control line; A: Position for detection of IgA and IgG anti-DGP; B: Position for detection of total IgA; CD: Celiac disease; IgA: Immunoglobulin A.

Figure 2 Histogram showing the immunoglobulin A-tissue transglutaminase enzyme-linked immunosorbent assay and celiac disease lateral-flow immunochromatographic assay test results. Text in gray indicates false-positive and false-negative results by celiac disease lateral-flow immunochromatographic assay (CD-LFIA). FDR: First-degree relatives; GFD: Gluten-free diet; Control: First-degree relatives and patients with celiac disease symptoms diagnosed as celiac disease (CD)-negative; IgA-tTG: Immunoglobulin A-tissue transglutaminase.

Figure 3 Diagnostic performance of the celiac disease lateral-flow immunochromatographic assay test determined by receiver operating characteristic curve analysis. A: GFD, FDR and CD symptoms; B: FDR and CD symptoms. FDR: First-degree relatives; CD: Celiac disease symptoms; GFD: Gluten-free diet; ROC: Receiver operating characteristic.