Brief Article
Copyright ©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Dec 14, 2011; 17(46): 5123-5130
Published online Dec 14, 2011. doi: 10.3748/wjg.v17.i46.5123
Figure 1
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Figure 1 Impact of 6th and 7th International Union Against Cancer N staging systems (A and B) and metastatic lymph node ratio staging (C) on overall survival of gastric cancer patients who underwent radical resection. A: The 6th International Union Against Cancer (UICC) N staging: N0 vs N1, P < 0.001; N1 vs N2, P < 0.001; N2 vs N3, P = 0.143; B: The 7th UICC N staging: N0 vs N1, P < 0.001; N1 vs N2, P = 0.003; N2 vs N3, P = 0.001; C: Metastatic lymph node ratio (MLNR) staging: MLNR0 vs MLNR1, P < 0.001; MLNR1 vs MLNR2, P < 0.001; MLNR2 vs MLNR3, P < 0.001.
Figure 2
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Figure 2 Analysis of the 6th (A and B) and 7th (C and D) International Union Against Cancer N staging systems and metastatic lymph node ratio staging (E and F) stratified according to the number of lymph nodes retrieved. A: The 6th International Union Against Cancer (UICC) N staging in the ≤ 15 lymph nodes retrieved group: N0 vs N1, P < 0.001; N1 vs N2, P < 0.001; B: The 6th UICC N staging in the > 15 lymph nodes retrieved group: N0 vs N1, P = 0.008; N1 vs N2, P < 0.001; N2 vs N3, P = 0.720; C: The 7th UICC N staging in the ≤ 15 lymph nodes retrieved group: N0 vs N1, P < 0.001; N1 vs N2, P = 0.001; N2 vs N3, P < 0.001; D: The 7th UICC N staging in the > 15 lymph nodes retrieved group: N0 vs N1, P = 0.070; N1 vs N2, P = 0.433; N2 vs N3, P < 0.001; E: Metastatic lymph node ratio (MLNR) stage in the ≤ 15 lymph nodes retrieved group: MLNR0 vs MLNR1, P = 0.001; MLNR1 vs MLNR2, P < 0.001; MLNR2 vs MLNR3, P < 0.001; F: MLNR stage in the > 15 lymph nodes retrieved group: MLNR0 vs MLNR1, P = 0.001; MLNR1 vs MLNR2, P < 0.001; MLNR2 vs MLNR3, P = 0.038.
Figure 3
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Figure 3 Receiver operating characteristics curve of the 6th and 7th edition International Union Against Cancer N staging systems and metastatic lymph node ratio staging for predicting survival of gastric cancer patients with radical resection. Area under the curve (AUC) of 1.0 represents a “perfect” diagnostic test that lacks false negative and false positive results. The AUC for the 6th and 7th edition International Union Against Cancer (UICC) N staging systems and metastatic lymph node ratio (MLNR) staging was 0.692, 0.705 and 0.754, respectively.