Original Articles
Copyright ©2009 The WJG Press and Baishideng.
World J Gastroenterol. Jun 21, 2009; 15(23): 2862-2869
Published online Jun 21, 2009. doi: 10.3748/wjg.15.2862
Figure 1
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Figure 1 Pathological changes in spleen of model control group (A) and treatment group (B). A1: 21 d. Spleen (++) (Bax, × 200); A2: 28 d. Thickening of the wall of small spleen arteries as well as expansion and congestion of the red pulp (HE, × 200); A3: 28 d. Enlargement of spleen sinusoid, hyperplasia of cells in the spleen sinus as well as inflammatory cell infiltration and hemorrhage (HE, × 200); A4: 28 d. Enlargement of spleen sinusoid and hyperplasia of fibrous tissue (HE, × 100); B1: 21 d. Spleen (+) (Bax, × 200); B2: 28 d. Focal necrosis in spleen lymphoid follicles (HE, × 100).
Figure 2
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Figure 2 Pathological changes in lymph nodes of sham-operating group (A), model control group (B), and treatment group (C). A1: 28 d. Mainly normal lymph nodes (HE, × 200); A2: 28 d. No apoptotic cells in lymph node (TUNEL, × 200); B1: 21 d. Focal necrosis in lymphoid follicles and formation of germinal centers (HE, × 200); B2: 21 d. Expansion of lymph sinus, sinus cell hyperplasia and inflammatory cell infiltration (HE, × 200); B3: 28 d. Enlargement and spotty necrosis in germinal centers of lymph nodes, expansion of lymph sinus, hyperplasia of sinus cells and infiltration of neutrophils in lymph sinus (HE, × 200); C: 28 d. Clear follicular structure and fewer necrotic spots in lymph nodes (HE, × 100).
Figure 3
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Figure 3 Pathological changes in thymus of sham-operated group (A), model control group (B), and treatment group (C). A1: 28 d. Clear structure of thymus lobules and a clear boundary between thymus cortex and medulla (HE, × 100); B1: 7 d. Sporadic apoptotic cells in thymus (TUNEL, × 400); B2: 21 d. Thymus (++) (NF-κB p65, × 200); B3: 28 d. An obscure boundary between the thymus cortex and medulla with hemorrhage in the medulla (HE, × 200); B4: 28 d. Thymus (++) (Bax, × 200); B5: 28 d. Sporadic apoptotic cells in thymus (TUNEL, × 400); C1: 21 d. Thymus (not shown) (NF-κB p65, × 200); C2: 28 d. Normal thymus (HE, × 200); C3: 28 d. Sporadic apoptotic cells in thymus (TUNEL, × 400).