Comparative proteomics analysis of human gastric cancer

Figure 1 2-DE maps of human gastric tissue separated by IPG with different pH intervals (silver staining). A and B: Normal and cancer tissues of stomach separated by pH 3-10 IPG strips; C and D: Normal and cancer tissues of stomach separated by pH 5-8 IPG strips; E and F: Normal and cancer tissues of stomach separated by pH 4-7 IPG strips.

Figure 2 Up-regulation of T8 (Zinc finger protein 134, indicated by vertical arrows) and down-regulation of N4 (Bullous pemphigoid antigen 1 isoforms 6/9/10, indicated by horizontal arrows) in gastric cancer tissue of four patients.

Figure 3 A: MALDI-TOF-TOF mass spectrum of the mixture of tryptic peptides derived from T8 (Actin, alpha cardiac); B: Matching of protein spot T8 (Actin, alpha cardiac) Peptide Mass Fingerprint data with protein P04270 in database.

Figure 4 MALDI-TOF mass spectrum of the mixture of tryptic peptides derived from N4 (Bullous pemphigoid antigen 1 isoforms 6/9/10).