Brief Reports
Copyright ©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Feb 14, 2005; 11(6): 880-884
Published online Feb 14, 2005. doi: 10.3748/wjg.v11.i6.880
Figure 1
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Figure 1 Amino acid sequence characteristics of CagA variable region. CZU-1,2,3: Isolates from Chinese patients stand for the three types of CagA variable region respectively; CZU-1: CagA with 2 EPIYAs; CZU-2: CagA with 3 EPIYAs and CZU-3: CagA with 4 EPIYAs. The red letters stand for the deletion of amino acids in CZU-1 and the letters underline the mean extra amino acids in CZU-3 when compared to CZU-2. NCTC11637 was a Western standard strain.
Figure 2
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Figure 2 Tyrosine phosphorylation sites in EPIYA in vitro and in vivo. A-F: tyrosine phosphorylation in vitro. Lane A: CagA with 4 EPIYAs; lane B: CagA with 3 EPIYAs; lane C: CagA with 2 EPIYAs; lane D: EPIFA with 1 EPIYA; lane E: EPIFA with 2 EPIYAs; lane F: EPIFA with 3 EPIYAs. lane G-L: tyrosine phosphorylation in vivo. G: CagA with 4 EPIYAs; H: CagA with 3 EPIYAs; I: CagA with 2 EPIYAs; lane J: EPIFA with 3 EPIYAs; lane K: EPIFA with 2 EPIYAs; lane L: EPIFA with 1 EPIYA.