Modulation of gastric accommodation by duodenal nutrients

Figure 1 Gastric relaxatory response to duodenal nutrients. Values are mean±SE. Note the saturable dose-related gastric relaxation with lipids, and a significantly weaker response with carbohydrates. ^aP<0.05 vs carbohydrates.

Figure 2 Example of gastric relaxation induced by duodenal lipid infusion (0. 2 kcal/mL). Gastric relaxation was measured as intra-gastric volume increment at constant pressure by a barostat. Note rapid relaxation and complete recovery after the infusion.

Figure 3 Perception of duodenal nutrient loads. All nutrient loads were unperceived, despite the prominent gastric accommodative response associate to some of them.