Novel DNA vaccine based on hepatitis B virus core gene induces specific immune responses in Balb/c mice

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Aug 7, 2005 (publication date) through Apr 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 7, 2005; 11(29): 4583-4586
Published online Aug 7, 2005. doi: 10.3748/wjg.v11.i29.4583

Figure 1 Digestion of pSW3891/HBc. Marker: λ/Hind III; C6, C7: clone no.

Figure 2 In vitro HBc expression in pSW3891/HBc transiently transfected 293T cells. V: pSW3891; L: lysate; C6: pSW3891/HBc/C6; S: supernatant.

Figure 3 End-point titres of anti-HBc in sera of Balb/c mice immunized with pSW3891/HBc.

Figure 4 Specific cytotoxicity of splenocytes inBalb/c mice immunized with pSW3891/HBc.

Citation: Xing YP, Huang ZH, Wang SX, Cai J, Li J, Chou THW, Lu S. Novel DNA vaccine based on hepatitis B virus core gene induces specific immune responses in Balb/c mice. World J Gastroenterol 2005; 11(29): 4583-4586
URL: https://www.wjgnet.com/1007-9327/full/v11/i29/4583.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i29.4583