Effects and possible anti-tumor immunity of electrochemotherapy with bleomycin on human colon cancer xenografts in nude mice

Figure 1 Mean tumor volume before and after treatment: group B-E-, no treatment; B+E-, administration of bleomycin alone; B-E+, administration of electric pulses alone; B+E+, ECT.

Figure 2 Histological examination of colon cancer xenografts on the 7^th d after treatment (hematoxylin and eosin staining). A: (group B-E-), B: (group B-E+) and C: (group B+E-) contained markedly atypical cells arranged irregularly; D: (group B+E+) exhibited massive necrosis with a moderately intense mononuclear infiltration (40×).