Viral Hepatitis
Copyright ©The Author(s) 2004.
World J Gastroenterol. Jun 1, 2004; 10(11): 1578-1582
Published online Jun 1, 2004. doi: 10.3748/wjg.v10.i11.1578
Math 1
Math 1 Math(A1).
Figure 1
Figure 1 Morphology of dendritic cells after 7 and 9 d. A: Cluster of DCs after 9 d (light microscope, × 100) ; B: A DC on day 7 (scanning electron microscope, × 5000) ; C: A DC on day 7 (transmitting electron microscope, × 5000).
Figure 2
Figure 2 Effect of TNF-α on DC secretion of IL-12.
Figure 3
Figure 3 MLR of DCs against allogeneic T cells.
Figure 4
Figure 4 Cytokine secretion of peptide-reactive T cells induced by DCs from one CHB patient. T cells from one CHB patient was incubated with autologous DCs pulsed with the HBV-specific peptide HBcAg 18-27 (Peptide) or without peptide (No peptide), and T cell response was detected by flow cytometry by measuring cytokine secretion by the activated T cells. The dot-plots show levels of intracellular staining for IFN-γ, IL-2 and TNF-α (y-axis) and surface CD8 molecule (x-axis). The number in the upper-right quadrant indicates the percentage of CD8-positive T cells that secret cytokines.
Figure 5
Figure 5 T cell cytotoxicity induced by DCs in CHB patients. DC+pep+T: T cells induced by DCs loaded with specific peptide; DC+T: T cells induced by DCs without peptide; T2+pep: pep-tide-loaded target cells; T2: target cells.