Dendritic cells from chronic hepatitis B patients can induce HBV antigen-specific T cell responses

Figure 4 Cytokine secretion of peptide-reactive T cells induced by DCs from one CHB patient. T cells from one CHB patient was incubated with autologous DCs pulsed with the HBV-specific peptide HBcAg 18-27 (Peptide) or without peptide (No peptide), and T cell response was detected by flow cytometry by measuring cytokine secretion by the activated T cells. The dot-plots show levels of intracellular staining for IFN-γ, IL-2 and TNF-α (y-axis) and surface CD8 molecule (x-axis). The number in the upper-right quadrant indicates the percentage of CD8-positive T cells that secret cytokines.