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World J Gastroenterol. Nov 14, 2026; 32(42): 120663
Published online Nov 14, 2026. doi: 10.3748/wjg.120663
Published online Nov 14, 2026. doi: 10.3748/wjg.120663
Clinical characteristics and endoscopic management of inflammatory fibroid polyp of the gastrointestinal tract
Chen-Huan Wang, Department of Gastroenterology and Hepatology, The First Medical Center, Chinese People’s Liberation Army General Hospital, Beijing 100853, China
Fang Liu, Long-Song Li, Ning-Li Chai, Department of Gastroenterology, The First Medical Center of Chinese PLA General Hospital, Beijing 100853, China
Xin-Hua Ji, Department of Pathology, The First Medical Center, Chinese People’s Liberation Army General Hospital, Beijing 100853, China
Co-first authors: Chen-Huan Wang and Fang Liu.
Co-corresponding authors: Long-Song Li and Ning-Li Chai.
Author contributions: Wang CH and Liu F contributed equally to this article, they are the co-first authors of this manuscript; Wang CH, Liu F, and Ji XH collected the data and conducted follow-up; Wang CH drafted the initial manuscript; Li LS and Chai NL critically revised the manuscript for important intellectual content and finally approved the version to be published, they contributed equally to this article, they are the co-corresponding authors of this manuscript; and all authors reviewed and approved the final manuscript.
Institutional review board statement: This study was approved by the Medical Ethics Committee of Chinese People’s Liberation Army General Hospital, approval No. S2023-115-01.
Informed consent statement: Informed consent was obtained from all individual participants included in the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The datasets analyzed during the current study are not publicly available due to data security policy but are available from the corresponding author on reasonable request.
Corresponding author: Ning-Li Chai, MD, Chief Physician, Professor, Department of Gastroenterology, The First Medical Center of Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, Beijing 100853, China. chainingli@vip.163.com
Received: March 5, 2026
Revised: April 1, 2026
Accepted: May 6, 2026
Published online: November 14, 2026
Processing time: 201 Days and 15.3 Hours
Revised: April 1, 2026
Accepted: May 6, 2026
Published online: November 14, 2026
Processing time: 201 Days and 15.3 Hours
Core Tip
Core Tip: Inflammatory fibroid polyps (IFPs) are rare gastrointestinal mesenchymal lesions with non-specific clinical and endoscopic features. This largest single-center cohort study of endoscopically treated IFPs confirms that ER is a safe and effective first-line treatment for IFPs, with high en bloc and complete resection rates. IFPs also show no specific features under endoscopic ultrasonography. Gastric IFPs tend to be larger and require more complex endoscopic resection techniques than colorectal IFPs.