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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 28, 2022; 28(36): 5240-5249
Published online Sep 28, 2022. doi: 10.3748/wjg.v28.i36.5240
Published online Sep 28, 2022. doi: 10.3748/wjg.v28.i36.5240
SARS-CoV-2 and the pancreas: What do we know about acute pancreatitis in COVID-19 positive patients?
Giuseppe Brisinda, Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome 00168, Italy
Giuseppe Brisinda, Department of Medicine and Surgery, Università Cattolica del Sacro Cuore, Rome 00168, Italy
Maria Michela Chiarello, Department of Surgery, Azienda Sanitaria Provinciale di Cosenza, Cosenza 87100, Italy
Giuseppe Tropeano, Gaia Altieri, Caterina Puccioni, Pietro Fransvea, Valentina Bianchi, Emergency Surgery and Trauma Center, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome 00168, Italy
Author contributions: Brisinda G and Chiarello MM equally contributed to the drafting of the manuscript and must both be considered first author; Chiarello MM and Brisinda G conceived the original idea; Tropeano G, Alteri G, Puccioni C, Fransvea P and Bianchi V performed a comprehensive review of all available literature and summarized the data; Brisinda G and Chiarello MM meet the criteria for authorship established by the International Committee of Medical Journal Editors and verify the validity of the results reported; and all authors read and approved the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Giuseppe Brisinda, MD, Professor, Surgeon, Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario A Gemelli IRCCS, Largo Agostino Gemelli 8, Rome 00168, Italy. gbrisin@tin.it
Received: May 17, 2022
Peer-review started: May 17, 2022
First decision: June 19, 2022
Revised: June 23, 2022
Accepted: September 8, 2022
Article in press: September 8, 2022
Published online: September 28, 2022
Peer-review started: May 17, 2022
First decision: June 19, 2022
Revised: June 23, 2022
Accepted: September 8, 2022
Article in press: September 8, 2022
Published online: September 28, 2022
Core Tip
Core Tip: The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing a severe acute respiratory syndrome, has rapidly spread from China all over the world, affecting millions of people. Whereas typical presentations of this infection (such as fever, cough, myalgia, fatigue and pneumonia) are well recognized, several studies report a low incidence of gastrointestinal symptoms. The relationship between SARS-CoV-2 infection and acute pancreatitis is controversial. Acute pancreatitis is not specifically caused by SARS-CoV-2. Furthermore, coronavirus disease 2019 positive patients are more likely to develop severe acute pancreatitis and multiple organ failure.