Retrospective Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 14, 2022; 28(30): 4163-4173
Published online Aug 14, 2022. doi: 10.3748/wjg.v28.i30.4163
Changes in the esophagogastric junction outflow obstruction manometric feature based on the Chicago Classification updates
Yue-Yuan Li, Wen-Ting Lu, Jian-Xiang Liu, Li-Hong Wu, Meng Chen, Hong-Mei Jiao
Yue-Yuan Li, Wen-Ting Lu, Meng Chen, Hong-Mei Jiao, Department of Geriatrics, Peking University First Hospital, Beijing 100034, China
Jian-Xiang Liu, Li-Hong Wu, Department of Gastroenterology and Hepatology, Peking University First Hospital, Beijing 100034, China
Author contributions: Li YY and Lu WT contributed equally to this work; Li YY, Lu WT, and Jiao HM conception and designed of research; Li YY and Lu WT analyzed data; Lu WT and Chen M performed the HRM and provided clinical information; Li YY, Liu JX, and Jiao HM interpreted of research; Li YY drafted manuscript; Jiao HM revised manuscript and approved the final version of manuscript; all authors approved the final version of the article.
Supported by the China Central Health Research Fund, No. W2013BJ29; and the Interdisciplinary Clinical Research Project of Peking University First Hospital, No.2019CR40.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Board of the Peking University First Hospital, No. 2022-099.
Informed consent statement: A waiver of informed consent was granted by our Institutional Review Board because our retrospective analysis used completely anonymized data.
Conflict-of-interest statement: All authors have declared no conflicts of interest.
Data sharing statement: Data sharing available, please require through email.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Hong-Mei Jiao, MD, Chief Physician, Department of Geriatrics, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing 100034, China.
Received: March 10, 2022
Peer-review started: March 10, 2022
First decision: April 11, 2022
Revised: April 21, 2022
Accepted: July 18, 2022
Article in press: July 18, 2022
Published online: August 14, 2022
Processing time: 152 Days and 16.5 Hours
Core Tip

Core Tip: This is a retrospective study to evaluate the motility features of esophagogastric junction outflow obstruction (EGJOO). This is the first detailed study of EGJOO based on the latest Chicago Classification. Patients with EGJOO showed more substantial abnormalities at the esophagogastric junction than patients who met the previous criteria, and the motility disorder of EGJOO is implicated in the proximal esophagus. Additionally, the upper esophageal sphincter nadir pressure, proximal esophageal contractile integral, proximal esophageal length, lower esophageal sphincter resting pressure, and integrated relaxation pressure on rapid drink challenge contribute to confirming the diagnosis of EGJOO.