Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 28, 2022; 28(28): 3586-3594
Published online Jul 28, 2022. doi: 10.3748/wjg.v28.i28.3586
Update on endoscopic ultrasound-guided liver biopsy
Shiva Rangwani, Devarshi R Ardeshna, Khalid Mumtaz, Sean G Kelly, Samuel Y Han, Somashekar G Krishna
Shiva Rangwani, Devarshi R Ardeshna, Khalid Mumtaz, Sean G Kelly, Samuel Y Han, Somashekar G Krishna, Division of Gastroenterology, Hepatology, and Nutrition,Department of Internal Medicine, Ohio State University Wexner Medical Center, Columbus, OH 43210, United States
Author contributions: Rangwani S and Ardeshna DR performed the majority of the literature search, writing, and preparation of tables; Mumtaz K, Kelly SG, and Han SY reviewed the final manuscript; Krishna SG provided figures, input in the writing process, and review of the final manuscript.
Conflict-of-interest statement: All authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Somashekar G Krishna, AGAF, FACG, FASGE, MD, Professor, Division of Gastroenterology, Hepatology, and Nutrition, Ohio State University Wexner Medical Center, 395 W 12th Avenue, Suite 262, Columbus, OH 43210, United States.
Received: January 16, 2022
Peer-review started: January 16, 2022
First decision: March 8, 2022
Revised: April 21, 2022
Accepted: June 23, 2022
Article in press: June 23, 2022
Published online: July 28, 2022
Core Tip

Core Tip: Endoscopic ultrasound guided liver biopsy (EUS-LB) has emerged as a minimally invasive alternative to the traditional (percutaneous or transjugular) liver biopsy techniques for the diagnosis of liver parenchymal diseases. EUS-LB facilitates access to both the lobes of the liver and allows measurement of portal pressure. EUS-LB has comparable diagnostic accuracy, increased yield of complete portal tracts, and longer specimen length compared to the traditional approaches. Innovations in needle technology and variations in suction have further optimized the EUS-LB technique. This review article updates current literature comparing EUS-LB to traditional liver biopsy and advances in this field.