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Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 7, 2021; 27(29): 4862-4878
Published online Aug 7, 2021. doi: 10.3748/wjg.v27.i29.4862
Muscular abnormalities in liver cirrhosis
Andrej Hari
Andrej Hari, Department of Gastroenterology and Hepatology, General Hospital Celje, Celje 3000, Savinjska, Slovenia
Author contributions: Hari A contributed to acquisition and interpretation of data, drafting the article and final approval of the version of the article to be published.
Conflict-of-interest statement: The author declare that he has no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Andrej Hari, MD, Doctor, Department of gastroenterology and hepatology, General hospital Celje, Oblakova ulica 5, Celje 3000, Savinjska, Slovenia. andrej.hari@sb-celje.si
Received: March 7, 2021
Peer-review started: March 7, 2021
First decision: April 17, 2021
Revised: April 19, 2021
Accepted: July 19, 2021
Article in press: July 19, 2021
Published online: August 7, 2021
Core Tip

Core Tip: Knowledge regarding the influence of sarcopenia in the course of chronic liver disease has greatly expanded in the past ten years, especially with respect to cirrhosis. Data show that it has a great influence on disease decompensation and patient mortality, providing clues for the development of newer evaluation modalities and sarcopenia indices. Nonetheless, data regarding the therapeutic consequences and interventions remain scarce. This article attempts to summarize the current state of knowledge of this important clinical topic with a critical evaluation of some related groundbreaking studies.