Systematic Reviews
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 21, 2021; 27(23): 3413-3428
Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3413
Local ablation of pancreatic tumors: State of the art and future perspectives
Vincenza Granata, Roberta Grassi, Roberta Fusco, Andrea Belli, Raffaele Palaia, Gianpaolo Carrafiello, Vittorio Miele, Roberto Grassi, Antonella Petrillo, Francesco Izzo
Vincenza Granata, Roberta Fusco, Antonella Petrillo, Department of Radiology, Istituto Nazionale Tumori –IRCCS- Fondazione G. Pascale, Naples 80131, Italy
Roberta Grassi, Department of Radiology, Università degli Studi della Campania Luigi Vanvitelli, Naples 80127, Italy
Andrea Belli, Raffaele Palaia, Francesco Izzo, Department of Surgery, Istituto Nazionale Tumori –IRCCS- Fondazione G. Pascale, Naples 80131, Italy
Gianpaolo Carrafiello, Department of Surgery, Università degli Studi di Milano, Milano 20122, Italy
Vittorio Miele, Roberto Grassi, Italian Society of Medical and Interventional Radiology SIRM, SIRM Foundation Milan 20122, Italy
Vittorio Miele, Department of Emergency Radiology, San Camillo Hospital, Firenze 50139, Italy
Roberto Grassi, Department of Radiology, Università degli Studi della Campania Luigi Vanvitelli, Naples 80127, Italy
Author contributions: Each author has participated sufficiently in any submission to take public responsibility for its content: Conceptualization; data curation; formal analysis; investigation; methodology; supervision; validation; visualization; roles/writing-original draft; and writing-review and editing.
Conflict-of-interest statement: No conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist statement, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Roberta Fusco, PhD, Technician, Department of Radiology, Istituto Nazionale Tumori –IRCCS- Fondazione G. Pascale, Via Mariano Semmola, Naples 80131, Italy. r.fusco@istitutotumori.na.it
Received: March 7, 2021
Peer-review started: March 7, 2021
First decision: March 27, 2021
Revised: March 28, 2021
Accepted: May 8, 2021
Article in press: May 8, 2021
Published online: June 21, 2021
Core Tip

Core Tip: In the current state of knowledge, the most commonly used technologies in locally advanced pancreatic cancer are radiofrequency ablation, microwave ablation, and irreversible or reversible electroporation combined with low doses of chemotherapeutic drugs. Our purpose is to report an updated overview of these techniques, highlighting the advantages and limitations of each technology.