Published online Apr 14, 2021. doi: 10.3748/wjg.v27.i14.1392
Peer-review started: January 10, 2021
First decision: February 11, 2021
Revised: February 23, 2021
Accepted: March 13, 2021
Article in press: March 13, 2021
Published online: April 14, 2021
Core Tip: Esophageal cancer (EC) is one of the most common malignant tumors of the digestive tract. Early EC lesions can be cured by endoscopic therapy, and the curative effect is equivalent to that of surgical operation. Upper gastrointestinal endoscopy is still the gold standard for EC diagnosis, while the accuracy of endoscopy depends in part on professional experience. Artificial intelligence applied in the screening of early EC has been shown to be a good assistant for those less-experienced endoscopists. This manuscript reviews the state of the art of artificial intelligence applications in clinical early EC detection by endoscopy for those who will be interested in this field.