Sleeve gastrectomy ameliorates endothelial function and prevents lung cancer by normalizing endothelin-1 axis in obese and diabetic rats
Rexiati Ruze, Ya-Cheng Xiong, Qian Xu, Department of General Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, Shandong Province, China
Jian-Wen Li, Department of General Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
Ming-Wei Zhong, Jian-Kang Zhu, Yu-Gang Cheng, San-Yuan Hu, Guang-Yong Zhang, Department of General Surgery, The First Affiliated Hospital of Shandong First Medical University, Jinan 250014, Shandong Province, China
Zhi-Bo Yan, Department of General Surgery, Qilu Hospital of Shandong University, Jinan 250012, Shandong Province, China
Author contributions: Zhang GY and Hu SY conceived of the experiments; Zhang GY and Li JW designed the experiments; Zhong MW, Zhu JK, and Cheng YG performed the literature research; Ruze R and Xiong YC carried out the experiments; Xu Q and Yan ZB performed the statistical analyses; Ruze R prepared the manuscript; Zhang GY gave final approval of the submitted and published versions.
Supported by National Natural Science Foundation of China, No. 81370496 and No. 81873647; Youth Program of National Natural Science Foundation of China, No. 81600059.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of The First Affiliated Hospital of Shandong First Medical University, Jinan, China (2020-S307).
Institutional animal care and use committee statement: All procedures involving animals were reviewed and approved by the Ethics Committee on Animal Experiment of The First Affiliated Hospital of Shandong First Medical University (2020-S307).
Conflict-of-interest statement: All authors declare that they have no conflicts of interest related to this study.
Data sharing statement: Research data of the current study is available at the Mendeley Data Depository, under: Ruzi, Rishat; Xiong, Yacheng; Li, Jianwen; Zhong, Mingwei; Xu, Qian; Yan, Zhibo; Zhu, Jiankang; Cheng, Yugang; Hu, Sanyuan; Zhang, Guangyong (2020), “Data for: Sleeve Gastrectomy Ameliorates Endothelial Function and Prevents Lung Cancer by Normalizing Endothelin-1 Axis and Reduces DNA damage in Obese and Diabetic Rats”, Mendeley Data, v3. http://dx.doi.org/10.17632/vj5469pmv6.3
ARRIVE guidelines statement: The authors have read the ARRIVE guidelines, and the manuscript was prepared and revised according to the ARRIVE guidelines.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Guang-Yong Zhang, DSc, MD, PhD, Chief Doctor, Professor, Department of General Surgery, The First Affiliated Hospital of Shandong First Medical University, No. 16766, Jingshi Road, Jinan 250014, Shandong Province, China. firstname.lastname@example.org
Received: March 14, 2020
Peer-review started: March 14, 2020
First decision: April 12, 2020
Revised: April 13, 2020
Accepted: May 15, 2020
Article in press: May 15, 2020
Published online: May 28, 2020