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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 7, 2020; 26(17): 2030-2039
Published online May 7, 2020. doi: 10.3748/wjg.v26.i17.2030
Published online May 7, 2020. doi: 10.3748/wjg.v26.i17.2030
Management of Barrett’s esophagus with dysplasia refractory to radiofrequency ablation
Kara L Raphael, Arvind J Trindade, Division of Gastroenterology, Long Island Jewish Medical Center, Zucker School of Medicine at Hofstra/Northwell, Northwell Health System, New Hyde Park, NY 11040, United States
Author contributions: Raphael KL performed data acquisition, drafted the manuscript and made critical revisions; Trindade AJ designed the outline, wrote the paper, made critical revisions, prepared the figures and tables, and gave final approval for publication.
Conflict-of-interest statement: There is no conflict of interest associated with any of the senior author or other coauthors contributed their efforts in this manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Arvind J Trindade, MD, Associate Professor, Director, Division of Gastroenterology, Long Island Jewish Medical Center, Zucker School of Medicine at Hofstra/Northwell, Northwell Health System, 270-05 76th Avenue, New Hyde Park, NY 11040, United States. arvind.trindade@gmail.com
Received: December 31, 2019
Peer-review started: December 31, 2019
First decision: April 1, 2020
Revised: April 8, 2020
Accepted: April 24, 2020
Article in press: April 24, 2020
Published online: May 7, 2020
Peer-review started: December 31, 2019
First decision: April 1, 2020
Revised: April 8, 2020
Accepted: April 24, 2020
Article in press: April 24, 2020
Published online: May 7, 2020
Core Tip
Core tip: This review highlights management strategies for patients with Barrett’s esophagus who are refractory to radiofrequency ablation therapy. A treatment algorithm is suggested that includes optimizing the radiofrequency ablation procedure, optimizing acid control, repeating radiofrequency ablation, and then using novel ablative or resection techniques for those patients with persistent refractory disease.