Meta-Analysis
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Apr 21, 2020; 26(15): 1820-1840
Published online Apr 21, 2020. doi: 10.3748/wjg.v26.i15.1820
Chemoprevention of gastric cancer development after Helicobacter pylori eradication therapy in an East Asian population: Meta-analysis
Mitsushige Sugimoto, Masaki Murata, Yoshio Yamaoka
Mitsushige Sugimoto, Department of Gastroenterological Endoscopy, Tokyo Medical University Hospital, Sinjuku, Tokyo 1600023, Japan
Masaki Murata, Department of Gastroenterology, National Hospital Organization Kyoto Medical Center, Kyoto 6128555, Japan
Yoshio Yamaoka, Department of Gastroenterology, Department of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu, Oita 8795593, Japan
Author contributions: Sugimoto M acquisition of data, analysis and interpretation of data, drafting the article, final approval; Murata M acquisition of data, analysis and interpretation of data, final approval; Yoshioka Y design of the study, final approval.
Conflict-of-interest statement: The authors deny any conflict of interest.
PRISMA 2009 Checklist statement: This study was conducted according to the PRISMA agreement reporting guidelines.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Mitsushige Sugimoto, MD, PhD, AGAF, Professor, Department of Gastroenterological Endoscopy, Tokyo Medical University Hospital, 6-7-1, Nishishinjuku, Shinjuku-ku, Tokyo 1600023, Japan. sugimo@tokyo-med.ac.jp
Received: December 16, 2019
Peer-review started: December 16, 2019
First decision: January 7, 2020
Revised: March 15, 2020
Accepted: April 1, 2020
Article in press: April 1, 2020
Published online: April 21, 2020
Core Tip

Core tip: No meta-analysis is available in the literature about the chemopreventive effects of Helicobacter pylori eradication therapy on the incidence of gastric cancer (GC) focused on East Asian populations living in geographical areas with high incidences of GC. We conducted a meta-analysis to reevaluate the prevention of Helicobacter pylori eradication therapy on the incidence of GC, irrespective of history of endoscopic or surgical treatment for GC.