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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 28, 2020; 26(12): 1352-1364
Published online Mar 28, 2020. doi: 10.3748/wjg.v26.i12.1352
Published online Mar 28, 2020. doi: 10.3748/wjg.v26.i12.1352
Pediatric living donor liver transplantation decade progress in Shanghai: Characteristics and risks factors of mortality
Zhi-Ying Pan, Yi-Chen Fan, Xiao-Qiang Wang, Ling-Ke Chen, Qiao-Qun Zou, Wei-Feng Yu, Dian-San Su, Department of Anesthesiology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China
Tao Zhou, Bi-Jun Qiu, Ye-Feng Lu, Yi Luo, Department of Liver Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China
Cong-Huan Shen, Department of Liver Transplantation, Huashan Hospital, School of Medicine, Shanghai Fudan University, Shanghai 200040, China
Author contributions: Pan ZY, Fan YC and Wang XQ contributed equally to this work; Su DS, Shen CH, Wang XQ, Pan ZY, Fan YC, Qiu BJ , Luo Y and Yu WF proposed the study conception; Su DS, Shen CH , Chen LK, Luo Y, Zhou T and Yu WF designed the study; Pan ZY, Fan YC, Wang XQ, Lu YF, Chen LK, Qiu BJ, Zhou T and Zou QQ conducted the study; Fan YC, Wang XQ, Shen CH and Pan ZY analyzed the data; Su DS, Pan ZY, Fan YC, Wang XQ, Lu YF, Shen CH, Zou QQ, Qiu BJ, Luo Y, Zhou T and Yu WF interpreted the data; Su DS, Pan ZY, Chen LK, Fan YC, Wang XQ, Lu YF, Zhou T , Luo Y and Zou QQ wrote the paper; Su DS, Luo Y, Lu YF, Pan ZY, Wang XQ, Fan YC, Chen LK, Yu WF, Qiu BJ, Zhou T and Zou QQ revised the paper.
Supported by the National Natural Science Foundation of China , No. 81571030, No. 81771133 and No. 81970995 ; Shanghai Pudong New Area Municipal Commission of Health and Family Planning Funding , No. PW2016D-4 ; Shanghai Jiao Tong University integration funding of Medicine and Engineering , No. YG2017MS53 ; and Shanghai Shenkang Hospital Development Center Funding , No. SHDC12017X11 .
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Renji Hospital, School of Medicine, Shanghai Jiaotong University.
Informed consent statement: This is a retrospective study and exemption of signed informed consent application had been approved by Renji Hospital Ethics Committee.
Conflict-of-interest statement: We have no financial relationships to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Dian-San Su, MD, PhD, Doctor, Professor, Department of Anesthesiology, Renji Hospital, Shanghai Jiaotong University, School of Medicine. 160 Pujian Road, Shanghai 200127, China. diansansu@yahoo.com
Received: November 24, 2019
Peer-review started: November 24, 2019
First decision: December 30, 2019
Revised: February 17, 2020
Accepted: February 28, 2020
Article in press: February 28, 2020
Published online: March 28, 2020
Peer-review started: November 24, 2019
First decision: December 30, 2019
Revised: February 17, 2020
Accepted: February 28, 2020
Article in press: February 28, 2020
Published online: March 28, 2020
Core Tip
Core tip: The annual caseload of pediatric living donor liver transplantation has been growing rapidly and recipients have achieved excellent outcomes in Shanghai with 2-year patient survival rate of 89.34%. Moreover, pediatric end-stage liver disease score, anesthesia duration, operation duration, intraoperative blood loss, and intensive care unit length of stay were independent predictive factors of in-hospital patient survival. Pediatric end-stage liver disease score, operation duration, and intensive care unit length of stay were independent predictive factors of 1-year and 3-year patient survival.