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World J Gastroenterol. Feb 21, 2019; 25(7): 777-788
Published online Feb 21, 2019. doi: 10.3748/wjg.v25.i7.777
Solutions for submucosal injection: What to choose and how to do it
Rui Castro, Diogo Libânio, Inês Pita, Mário Dinis-Ribeiro
Rui Castro, Diogo Libânio, Inês Pita, Mário Dinis-Ribeiro, Department of Gastroenterology, Portuguese Oncology Institute of Porto, Porto 4450-590, Portugal
Mário Dinis-Ribeiro, CIDES/CINTESIS, Faculty of Medicine, University of Porto, Porto 4200-319, Portugal
Author contributions: All authors equally contributed to this paper with conception and design of the study, literature review and analysis, drafting and critical revision and editing, and final approval of the final version.
Conflict-of-interest statement: No potential conflicts of interest. No financial support.
Open-Access: This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Rui Castro, MD, Doctor, Department of Gastroenterology, Portuguese Oncology Institute of Porto, Rua Dr. António Bernardino de Almeida, Porto 4450-590, Portugal. rui.arrais.castro@gmail.com
Telephone: +351-911592435
Received: November 14, 2018
Peer-review started: November 14, 2018
First decision: January 6, 2019
Revised: January 18, 2019
Accepted: January 26, 2019
Article in press: January 26, 2019
Published online: February 21, 2019
Core Tip

Core tip: In this work, we review the importance of submucosal injection and present some of the most commonly used solutions, comparing them taking into account their advantages and disadvantages. Unlike most of the previous papers about this subject, we organized this review in a more practical point of view. For that, we try to answer some essential questions like: what is the need for submucosal injection, when should we use it, what type of solution is more suitable for each endoscopic resection technique and how should we use them.