Histologic features and genomic alterations of primary colorectal adenocarcinoma predict growth patterns of liver metastasis
Jing-Bo Wu, Department of Pathology, The Fifth People’s Hospital, Fudan University, Shanghai 200240, China
Ali Lopez Sarmiento, Pierre-Olivier Fiset, Zu-Hua Gao, Department of Pathology, McGill University and the Research Institute of McGill University Health Center, Montreal H4A 3J1, Quebec, Canada
Anthula Lazaris, Peter Metrakos, Stephanie Petrillo, Cancer Research Program, The Research Institute of McGill University Health Center, Montreal H4A 3J1, Quebec, Canada
Author contributions: All authors helped to perform the research; Wu JB performed the research and wrote the paper; Sarmiento AL contributed to paper writing and data analysis; Fiset PO provided experimental advice; Lazaris A and Petrillo S contributed to the analysis of clinical data; Metrakos P contributed to the project design; Gao ZH designed the project and edited the manuscript.
Supported by the Human Resources Development Program for the Outstanding Talents in The Fifth People’s Hospital of Shanghai, Fudan University, No. 2017WYRCJY09; and the Key Medical Speciality of The Fifth People’s Hospital of Shanghai, Fudan University, No. 2017WY202K08.
Institutional review board statement: This study was reviewed and approved by McGill University Health Center Research Ethics Board, No. 11-066-SDR.
Informed consent statement: All patients in our study provided informed consent.
Conflict-of-interest statement: All authors declare no conflict of interest related to the article.
Data sharing statement: No additional data are available.
Open-Access: This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Zu-Hua Gao, FRCPC, MD, PhD, Professor, Department of Pathology, McGill University and the Research Institute of McGill University Health Center, Room E04.1820, 1001 Decarie Boulevard, Montreal H4A 3J1, Quebec, Canada. firstname.lastname@example.org
Received: March 18, 2019
Peer-review started: March 19, 2019
First decision: May 9, 2019
Revised: June 5, 2019
Accepted: June 7, 2019
Article in press: June 8, 2019
Published online: July 14, 2019