High expression of type I inositol 1,4,5-trisphosphate receptor in the kidney of rats with hepatorenal syndrome
Jing-Bo Wang, Ye Gu, Ming-Xiang Zhang, Yan Wang, Wei Wang, Xi-Ran Li, Yi-Tong Zhao, Liver Cirrhosis Ward, the Sixth People’s Hospital of Shenyang, Shenyang 110006, Liaoning Province, China
Shun Yang, Liaoning Cancer Hospital & Institute, Shenyang 110042, Liaoning Province, China
Hai-Tao Wang, Department of General Surgery, the Second Affiliated Hospital of Shenyang Medical College, Shenyang 110002, Liaoning Province, China
Author contributions: Wang JB, Wang HT and Gu Y contributed equally to this work, and all of them were involved in the design and performing of the experiment, data analysis and drafting of the article; Zhang MX, Wang Y and Yang S participated in the study, hepatic and renal pathological examination and biochemical test; Li XR, Wang W and Zhao YT completed data analysis, Western blot analysis and real-time PCR and drafting of the paper.
Supported by Natural Science Foundation of Liaoning Province, No. 20170540826; Science and Technology Program of Shenyang City, No. 18-014-4-49; and Innovation Support Program of Shenyang City for Young and Middle-Aged Researchers, No. RC170051.
Institutional animal care and use committee statement: This study was approved by the Ethical Committee of the Sixth People’s Hospital of Shenyang.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Hai-Tao Wang, MSc, Surgeon, Department of General Surgery, the Second Affiliated Hospital of Shenyang Medical College, No. 20, Beijiuma Road, Heping District, Shenyang 110002, Liaoning Province, China. email@example.com
Telephone: +86-18002452018 Fax: +86-24-31251510
Received: May 3, 2018
Peer-review started: May 4, 2018
First decision: June 6, 2018
Revised: June 19, 2018
Accepted: June 27, 2018
Article in press: June 27, 2018
Published online: August 7, 2018