Published online Jul 14, 2018. doi: 10.3748/wjg.v24.i26.2806
Peer-review started: March 28, 2018
First decision: May 9, 2018
Revised: June 3, 2018
Accepted: June 22, 2018
Article in press: June 22, 2018
Published online: July 14, 2018
Core tip: Potentially malignant gastrointestinal stromal tumors are the most common subepithelial lesions (SELs) of the gastrointestinal tract. SELs include a broader range of differential diagnoses from benign to malignant lesions. The possibility of having a malignant lesion may cause anxiety and discomfort in patients and gastroenterologists. Early and accurate diagnosis of SELs using endoscopic ultrasonography (EUS) and/or EUS-guided fine needle aspiration is vital to guide selection of early appropriate management.