Potential triggering factors of acute liver failure as a first manifestation of autoimmune hepatitis-a single center experience of 52 adult patients
Matthias Buechter, Paul Manka, Guido Gerken, Alisan Kahraman, Department of Gastroenterology and Hepatology, University Clinic of Essen, Essen 45147, Germany
Paul Manka, Division of Transplantation Immunology and Mucosal Biology, King’s College, London SE59RJ, United Kingdom
Falko Markus Heinemann, Monika Lindemann, Institute of Transfusion Medicine, University Clinic of Essen, Essen 45147, Germany
Hideo Andreas Baba, Martin Schlattjan, Institute of Pathology, University Clinic of Essen, Essen 45147, Germany
Ali Canbay, Department of Gastroenterology, Hepatology, and Infectious Diseases, Otto-von-Guericke University, Magdeburg 39120, Germany
Author contributions: Buechter M analyzed the data and wrote the manuscript; Manka P analyzed the data and performed the statistics; Heinemann FM and Lindemann M performed the HLA-typing; Baba HA and Schlattjan M evaluated the histological specimens; Canbay A and Gerken G treated the patients; Kahraman A treated the patients and designed the study.
Institutional review board statement: This study was reviewed and approved by the ethics committee of the University Clinic of Essen.
Informed consent statement: All patients gave their written informed consent prior to study inclusion.
Conflict-of-interest statement: All authors have nothing to declare.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Kahraman Alisan, MD, Associate Professor, Department of Gastroenterology and Hepatology, University Hospital of Essen, Hufelandstr 55, Essen 45122, Germany. firstname.lastname@example.org
Telephone: +49-201-72384797 Fax: +49-201-7235655
Received: December 6, 2017
Peer-review started: December 6, 2017
First decision: January 18, 2018
Revised: February 21, 2018
Accepted: March 3, 2018
Article in press: March 3, 2018
Published online: April 7, 2018