Molecular mechanisms of apoptosis in hepatocellular carcinoma cells induced by ethanol extracts of Solanum lyratum Thumb through the mitochondrial pathway
Xiao-Qiang Mo, Hong-Yu Wei, Gan-Rong Huang, Yu-Li Chen, Wei Xian, Yan-Chun Qin, Lian-Deng Wei, Li-Juan Zhao, Yan-Qiang Huang, Wei Xing, Hong-Qin Pu, Peng-Ya Wei, Chao-Gan Li, Qiu-chun Liang, Breeding Base of Microbial Infection Key Laboratory in the West Guangxi, Youjiang Medical University for Nationalities, Baise 533000, Guangxi Zhuang Autonomous Region, China
Ling-Yuan Xu, Jiang Qi, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise 533000, Guangxi Zhuang Autonomous Region, China
Author contributions: Mo XQ, Wei HY and Huang GR performed research and contributed equally to this work; Xu LY, Chen YL, Qi J, Xian W, Qin YC, Wei LD, Zhao LJ, Pu HQ, Wei PY, Li CG and Liang Qc analyzed the data; Huang YQ and Xing W designed the research, analyzed the data and contributed equally to this work; all authors drafted the article and made critical revisions related to the intellectual content of the manuscript, and approved the final version of the article to be published.
Supported by the Guangxi key disciplines (Pathogen Biology)  16, key laboratory cultivation base of universities in Guangxi (Guangxi Education Research  6); the science and technology research projects of universities in Guangxi in 2014, No. YB2014307; the Guangxi natural science fund project, No. 2013GXNSFAA019249, No. 2014GXNSFBA118148; and the Scientific Research Project of The Department of Education of Guangxi Zhuang Autonomous Region, No. 200810LX327.
Institutional review board statement: This study was reviewed by the Youjiang Medical University Institutional review board.
Conflict-of-interest statement: We declare that there are no conflicts of interest to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Yan-Qiang Huang, Professor, Breeding Base of Microbial Infection Key Laboratory in the West Guangxi, Youjiang Medical University for Nationalities, No. 98 Countryside Road, Baise 533000, Guangxi Zhuang Autonomous Region, China. email@example.com
Telephone: +86-776-2853272 Fax: +86-776-2853272
Received: September 25, 2016
Peer-review started: September 30, 2016
First decision: October 20, 2016
Revised: November 4, 2016
Accepted: November 23, 2016
Article in press: November 28, 2016
Published online: February 14, 2017