Levothyroxine therapy and impaired clearance are the strongest contributors to small intestinal bacterial overgrowth: Results of a retrospective cohort study
Thorsten Brechmann, Andre Sperlbaum, Wolff Schmiegel, Department of Gastroenterology and Hepatology, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil GmbH, Ruhr-University Bochum, 44789 Bochum, Germany
Author contributions: Brechmann T was guarantor of the article; contributed to conception and design of the study, data analysis and interpretation, supervision, drafting the manuscript; Sperlbaum A contributed to conducting the study, acquisition of data, analysis and interpretation; Schmiegel W contributed to supervision, revision of the manuscript, support in terms of gastroenterology; all authors approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of the Ruhr-University Bochum (Registration number: 4864-13).
Conflict-of-interest statement: The authors declare that there is no actual or potential conflict of interest related to the work.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Thorsten Brechmann, MD, Department of Gastroenterology and Hepatology, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil GmbH, Ruhr-University Bochum, Bürkle-de-la-Camp-Platz 1, 44789 Bochum, Germany. email@example.com
Telephone: +49-234-3023411 Fax: +49-234-3026707
Received: August 26, 2016
Peer-review started: August 28, 2016
First decision: October 20, 2016
Revised: October 22, 2016
Accepted: November 16, 2016
Article in press: November 16, 2016
Published online: February 7, 2017