Prostaglandin E1 protects hepatocytes against endoplasmic reticulum stress-induced apoptosis via protein kinase A-dependent induction of glucose-regulated protein 78 expression
Fang-Wan Yang, Yu Fu, Ying Li, Yi-Huai He, Mao-Yuan Mu, Qi-Chuan Liu, Jun Long, Shi-De Lin
Fang-Wan Yang, Yu Fu, Ying Li, Yi-Huai He, Mao-Yuan Mu, Qi-Chuan Liu, Jun Long, Shi-De Lin, Department of Infectious Diseases, Affiliated Hospital of Zunyi Medical College, Zunyi 563003, Guizhou Province, China
Yu Fu, Department of Infectious Diseases, Heze Municipal Hospital, Heze 274000, Shandong Province, China
Author contributions: Yang FW and Fu Y contributed equally to this work; Yang FW, Fu Y, Li Y and He YH performed the experiments; Mu MY and Liu QC participated equally in the molecular investigations; Long J supervised the study; Lin SD designed and coordinated the research and wrote the manuscript.
Supported by the National Natural Science Foundation of China, No. 81160067 and No. 814600124.
Institutional review board statement: This study was approved by the Institutional Review Board of Affiliated Hospital of Zunyi Medical College, Guizhou Province, China.
Conflict-of-interest statement: The authors declare that they have no conflicts interest related to this study.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at linshide6@hotmail.com.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Shi-De Lin, MD, Professor of Medicine, Chief, Department of Infectious Diseases, Affiliated Hospital of Zunyi Medical College, 201 Dalian Street, Zunyi 563003, Guizhou Province, China. linshide6@hotmail.com
Telephone: +86-851-28609183 Fax: +86-851-28609183
Received: May 11, 2017
Peer-review started: May 13, 2017
First decision: June 22, 2017
Revised: July 24, 2017
Accepted: August 25, 2017
Article in press: August 25, 2017
Published online: October 28, 2017
