Adipose-derived stromal cells resemble bone marrow stromal cells in hepatocyte differentiation potential in vitro and in vivo
Li-Juan Xu, Zheng Chen, Qian-Qian Chen, Li Yan, Department of Gastroenterology, Institute of Geriatrics, Chinese PLA General Hospital, Beijing 100853, China
Shu-Fang Wang, De-Qing Wang, Department of Blood Transfusion, Chinese PLA General Hospital, Beijing 100853, China
Lian-Jun Ma, Department of Endoscopics, China-Japan Union Hospital of Jilin University, Changchun 130000, Jilin Province, China
Jun Wang, Department of Gastroenterology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing 400042, China
Author contributions: Xu LJ, Wang SF performed the research, analyzed the data, and wrote and revised the paper; Wang DQ provided the experimental site; Ma LJ, Chen Z, Chen QQ performed the research; Wang J and Yan L designed the research and participated in the revision of the paper; Xu LJ, Wang SF contributed equally to this work; all authors have read and approved the final manuscript.
Supported by the National Natural Science Foundation of China, No. 30900669 and No. 81473271; Technology Nova Plan of Beijing City, No. 2011117; China Postdoctoral Science Foundation, No. 2016T90994.
Institutional review board statement: The study was reviewed and approved by the Ethics Committee of Chinese PLA General Hospital, Beijing, China.
Institutional animal care and use committee statement: All experiments on animals were performed in accordance with the “Guide for the Care and Use of Laboratory Animals” (National Institutes of Health, 8th ed. 2011). All procedures involving animals were reviewed and approved by the Animal Care and Research Committee of Chinese PLA General Hospital, Beijing, China.
Conflict-of-interest statement: All the authors declare no potential conflict of interest related to this paper.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Li Yan, MD, PhD, Department of Gastroenterology, Institute of Geriatrics, Chinese PLA General Hospital, No. 28 Wanshou Road, Haidian District, Beijing 100853, China. email@example.com
Telephone: +86-10-66876346 Fax: +86-10-66876346
Received: April 16, 2017
Peer-review started: April 27, 2016
First decision: June 22, 2017
Revised: July 20, 2017
Accepted: September 5, 2017
Article in press: September 5, 2017
Published online: October 14, 2017