Review
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 7, 2017; 23(33): 6030-6048
Published online Sep 7, 2017. doi: 10.3748/wjg.v23.i33.6030
Autoimmune hepatitis: Standard treatment and systematic review of alternative treatments
Benedetta Terziroli Beretta-Piccoli, Giorgina Mieli-Vergani, Diego Vergani
Benedetta Terziroli Beretta-Piccoli, Epatocentro Ticino, 6900 Lugano, Switzerland
Giorgina Mieli-Vergani, Paediatric Liver, GI and Nutrition Centre, MowatLabs, King’s College Hospital, Denmark Hill, London SE5 9RS, United Kingdom
Diego Vergani, Institute of Liver Studies, MowatLabs, King’s College Hospital, Denmark Hill, London SE5 9RS, United Kingdom
Author contributions: Terziroli Beretta-Piccoli B contributed to writing up the manuscript; Mieli-Vergani G and Vergani D contributed to critical revision and final approval of the report.
Conflict-of-interest statement: No potential conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Diego Vergani, Professor, Institute of Liver Studies, MowatLabs, King’s College Hospital, Denmark Hill, London SE5 9RS, United Kingdom. diego.vergani@kcl.ac.uk
Telephone: +44-20-32994643 Fax: +44-20-32994224
Received: June 6, 2017
Peer-review started: June 7, 2017
First decision: June 22, 2017
Revised: July 18, 2017
Accepted: August 2, 2017
Article in press: August 2, 2017
Published online: September 7, 2017
Core Tip

Core tip: The first part of this review summarizes the standard therapeutic approach for autoimmune hepatitis (steroids and azathioprine) and the evidence on which it is based. The second part reviews systematically published data on first and second line alternative treatments. This information is summarized in two comprehensive tables, one for adult and one for paediatric patients.