Detection and characterization of murine colitis and carcinogenesis by molecularly targeted contrast-enhanced ultrasound
Markus Brückner, Tobias M Nowacki, Friederike Cordes, Dominik Bettenworth, Department of Medicine B, University Hospital of Münster, D-48149 Münster, Germany
Jan Heidemann, Department of Gastroenterology, Klinikum Bielefeld Mitte, Academic Teaching Hospital, University of Münster, D-33604 Bielefeld, Germany
Jörg Stypmann, Department of Cardiology and Angiology, University Hospital of Münster, D-48149 Münster, Germany
Philipp Lenz, Department of Palliative Care, University Hospital of Münster, D-48149 Münster, Germany
Faekah Gohar, Department of Paediatric Rheumatology and Immunology, University Hospital of Münster, D-48149 Münster, Germany
Andreas Lügering, Medical Care Center Portal 10, D-48155 Münster, Germany
Author contributions: Brückner M and Heidemann J contributed equally to this work and share first authorship; Brückner M, Heidemann J, Lügering A and Bettenworth D contributed to the article design, literature search, manuscript writing and final revision of the article; Brückner M performed ultrasound examinations; Brückner M, Cordes F and Bettenworth D performed the research and analysed the data; Brückner M, Nowacki TM, Cordes F, Stypmann J, Lenz P and Gohar F contributed to manuscript writing and final revision of the article; Gohar F proofread the final revision.
Institutional review board statement: The study was reviewed and approved by the University Hospital of Münster - Department of Medicine B Institutional Review Board.
Institutional animal care and use committee statement: All procedures using animals were reviewed and approved by the local animal subjects committee, University of Münster (permit 84-02.04.2013.A093).
Conflict-of-interest statement: None of the authors has received fees for serving as a speaker or received research funding from with regard to this study. None of the authors owns stocks and/or shares with regards to this study. None of the authors owns patents with regard to this study.
Data sharing statement: Technical appendix, statistical code, and dataset are available from the corresponding author at email@example.com.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Markus Brückner, MD, Department of Medicine B, University Hospital of Münster, Albert-Schweitzer-Campus 1, D-48149 Münster, Germany. firstname.lastname@example.org
Telephone: +49-251-8347661 Fax: +49-251-8347570
Received: December 29, 2016
Peer-review started: December 30, 2016
First decision: February 23, 2017
Revised: March 14, 2017
Accepted: March 30, 2017
Article in press: March 30, 2017
Published online: April 28, 2017