Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 14, 2016; 22(6): 2046-2059
Published online Feb 14, 2016. doi: 10.3748/wjg.v22.i6.2046
Glucose metabolism in gastric cancer: The cutting-edge
Lian-Wen Yuan, Hiroharu Yamashita, Yasuyuki Seto
Lian-Wen Yuan, Department of Geriatric Surgery, Second Xiangya Hospital, Center-South University, Changsha 410011, Hunan Province, China
Lian-Wen Yuan, Hiroharu Yamashita, Yasuyuki Seto, Department of Gastrointestinal Surgery, Graduate School of Medicine, University of Tokyo, Tokyo 113-8655, Japan
Author contributions: Yuan LW performed the literature search and wrote the review; Yamashita H and Seto Y participated in revising the review.
Supported by The China Scholarship Council, No. [2014]3012.
Conflict-of-interest statement: The authors declare that they have no competing interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Lian-Wen Yuan, MD, PhD, Associate Professor, Visiting Researcher, Department of Geriatrics Surgery, Second Xiangya Hospital, Center-South University, Yuelu District, 932 South Lushan Rd, Changsha 410011, Hunan Province, China.
Telephone: +86-731-85295167 Fax: +86-731-5362966
Received: June 20, 2015
Peer-review started: June 25, 2015
First decision: July 10, 2015
Revised: September 18, 2015
Accepted: November 30, 2015
Article in press: November 30, 2015
Published online: February 14, 2016
Core Tip

Core tip: Increased glucose consumption is a hallmark of cancer cells. Studies focusing on glucose metabolism provide a new perspective on gastric carcinogenesis and a novel approach to exploration of biomarkers and therapeutic targets in gastric cancer.