Visceral hypersensitivity in inflammatory bowel diseases and irritable bowel syndrome: The role of proteases
Hannah Ceuleers, Hanne Van Spaendonk, Nikita Hanning, Jelena Heirbaut, Joris G De Man, Benedicte Y De Winter, Laboratory of Experimental Medicine and Pediatrics, Division of Gastroenterology, University of Antwerp, 2610 Antwerp, Belgium
Anne-Marie Lambeir, Ingrid De Meester, Laboratory of Medical Biochemistry, University of Antwerp, 2610 Antwerp, Belgium
Jurgen Joossens, Koen Augustyns, Laboratory of Medicinal Chemistry and Antwerp Drug Discovery Network, University of Antwerp, 2610 Antwerp, Belgium
Author contributions: All authors contributed equally to this paper with conception and design of the study, literature review and analysis, drafting and critical review and editing and approval of the final version.
Supported by University Research Fund Doctoral Projects (BOF-DOCPRO), No. DOCPRO4 2014/ID 2964; and Research Foundation Flanders (FWO), No. G034113N.
Conflict-of-interest statement: No potential conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Benedicte Y De Winter, Professor, MD, PhD, Laboratory of Experimental Medicine and Pediatrics, Division of Gastroenterology, University of Antwerp, Universiteitsplein 1, 2610 Antwerpen, Belgium. firstname.lastname@example.org
Telephone: +32-3-2652710 Fax: +32-3-2652567
Received: September 21, 2016
Peer-review started: September 22, 2016
First decision: October 20, 2016
Revised: November 10, 2016
Accepted: December 2, 2016
Article in press: December 2, 2016
Published online: December 21, 2016